Introduction to the cellular and molecular biology of cancer
Başlık:
Introduction to the cellular and molecular biology of cancer
ISBN:
9780198525639
Yazar:
Basım Bilgisi:
4. bs.
Yayım Bilgisi:
New York : Oxford University Press , 2005.
Fiziksel Açıklamalar:
xvii, 532 s. : şkl. ; 25 cm.
Genel Not:
Contents Contributors xv Abbreviation 00 Glossary 00 1 What is cancer? 1 L. M. Franks and M. A. Knowles 2 The causes of cancer 25 Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key. 3 Inherited susceptibility to cancer 45 D. Timothy Bishop 4 DNA repair and cancer 61 Beate Köberle, John P. Wittschieben, and Richard D. Wood 5 Epigenetic events in cancer 78 Jonathan C. Cheng and Peter A. Jones 6 Molecular cytogenetics of cancer 96 Denise Sheer and Janet Shipley 7 Oncogenes 118 Margaret A. Knowles 8 Tumour suppressor genes 136 Sonia Laín and David P. Lane 9 The cancer cell cycle 157 Chris J. Norbury 10 Cellular immortalization and telomerase activation in cancer 171 Robert F. Newbold 11 Growth factors and their signalling pathways in cancer 187 Sally A. Prigent 12 Apoptosis: molecular physiology and significance for cancer therapeutics 211 Dean A. Fennell 13 Mechanisms of viral carcinogenesis 230 Paul Farrell 14 Cytokines and cancer 243 Peter W. Szlosarek and Frances R. Balkwill 15 Hormones and cancer 258 Charlotte L. Bevan 16 The spread of tumours 279 Ian Hart 17 Cellular and molecular biology of cancer: Angiogenesis 290 K. Tahtis and R. Bicknell 18 Stem cells, haemopoiesis, and leukaemia 306 Mel Greaves 19 Animal models of cancer 318 Jos Jonkers and Anton Berns 20 The immunology of cancer 338 Peter C. L. Beverley 21 The Molecular pathology of cancer 357 Tatjana Crnogorac-Jurcevic, Richard Poulsom, and Nicholas R. Lemoine 22 From transcriptome to proteome 370 Silvana Debernardi, Rachel Craven, Bryan D. Young, and Rosamonde E. Banks 23 Local treatment of cancer 391 I. S. Fentiman 24 Chemotherapy 400 D. R. Camidge and D. I. Jodrell 25 Radiotherapy and molecular radiotherapy 415 Anne Kiltie 26 Monoclonal antibodies and therapy 429 T. Geldart, M. J. Glennie, and P. W. M. Johnson 27 Immunotherapy of cancer 444 Andrew M. Jackson and Joanne Porte 28 Cancer gene therapy 459 John David Chester 29 Screening 481 Peter Sasieni and Jack Cuzick 30 Conclusions and prospects 504 Peter Selby and Margaret Knowles
Özet:
Contents Contributors xv Abbreviation 00 Glossary 00 1 What is cancer? 1 L. M. Franks and M. A. Knowles 2 The causes of cancer 25 Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key. 3 Inherited susceptibility to cancer 45 D. Timothy Bishop 4 DNA repair and cancer 61 Beate Köberle, John P. Wittschieben, and Richard D. Wood 5 Epigenetic events in cancer 78 Jonathan C. Cheng and Peter A. Jones 6 Molecular cytogenetics of cancer 96 Denise Sheer and Janet Shipley 7 Oncogenes 118 Margaret A. Knowles 8 Tumour suppressor genes 136 Sonia Laín and David P. Lane 9 The cancer cell cycle 157 Chris J. Norbury 10 Cellular immortalization and telomerase activation in cancer 171 Robert F. Newbold 11 Growth factors and their signalling pathways in cancer 187 Sally A. Prigent 12 Apoptosis: molecular physiology and significance for cancer therapeutics 211 Dean A. Fennell 13 Mechanisms of viral carcinogenesis 230 Paul Farrell 14 Cytokines and cancer 243 Peter W. Szlosarek and Frances R. Balkwill 15 Hormones and cancer 258 Charlotte L. Bevan 16 The spread of tumours 279 Ian Hart 17 Cellular and molecular biology of cancer: Angiogenesis 290 K. Tahtis and R. Bicknell 18 Stem cells, haemopoiesis, and leukaemia 306 Mel Greaves 19 Animal models of cancer 318 Jos Jonkers and Anton Berns 20 The immunology of cancer 338 Peter C. L. Beverley 21 The Molecular pathology of cancer 357 Tatjana Crnogorac-Jurcevic, Richard Poulsom, and Nicholas R. Lemoine 22 From transcriptome to proteome 370 Silvana Debernardi, Rachel Craven, Bryan D. Young, and Rosamonde E. Banks 23 Local treatment of cancer 391 I. S. Fentiman 24 Chemotherapy 400 D. R. Camidge and D. I. Jodrell 25 Radiotherapy and molecular radiotherapy 415 Anne Kiltie 26 Monoclonal antibodies and therapy 429 T. Geldart, M. J. Glennie, and P. W. M. Johnson 27 Immunotherapy of cancer 444 Andrew M. Jackson and Joanne Porte 28 Cancer gene therapy 459 John David Chester 29 Screening 481 Peter Sasieni and Jack Cuzick 30 Conclusions and prospects 504 Peter Selby and Margaret Knowles
Ek Yazar: