Yönetmen : Paul Weitz Oyuncular : Jessica Alba, Robert De Niro, Ben Stiller, Owen Wilson, Dustin Hoffman Senaryo : John Hamburg, Larry Stuckey Yapımcı : Robert De Niro, Jane Rosenthal

Aradan geçen 10 yıl, karısı Pam'le (Polo) yaptıkları iki küçük Focker ve aşılan sayısız engelden sonar, Greg nihayet asabi kayınpederi Jack'in güvenini kazanır. Fakat para sıkıntısı çeken babamız, bir ilaç şirketinde ikinci bir işe girdiğinde, Jack'in en sevdiği erkek hemşireyle ilgili şüpheleri tekrar baş gösterir. It has taken 10 years, two little Fockers with wife Pam, and countless hurdles for Greg to finally get in with his tightly wound father-in-law, Jack. After the cash-strapped dad takes a job moonlighting for a drug company, however, Jack's suspicions about his favorite male nurse come roaring back. When Greg and Pam's entire clan--including Pam's lovelorn ex, Kevin (Owen Wilson)--descends for the twins' birthday party, Greg must prove to the skeptical Jack that he's fully capable as the man of the house. But with all the misunderstandings, spying, and covert missions, will Greg pass Jack's final test and become the family's next patriarch, or will the circle of trust be broken for good?